Protective Effects of Garlic Oil on Hepatocarcinoma Induced by N-Nitrosodiethylamine in Rats
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چکیده
منابع مشابه
Protective Effects of Garlic Oil on Hepatocarcinoma Induced by N-Nitrosodiethylamine in Rats
To investigate the protective effects and the possible mechanisms of garlic oil (GO) against N-nitrosodiethylamine (NDEA)-induced hepatocarcinoma in rats, Wistar rats were gavaged with GO (20 or 40 mg/kg) for 1 week, and then were gavaged with GO and NDEA (10 mg/kg) for the next 20 weeks. The changes of morphology, histology, the biochemical indices of serum, and DNA oxidative damage of liver w...
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To explore the underlying mechanisms for the protective effects of garlic oil (GO) against nitrosodiethylamine (NDEA)-induced hepatocarcinoma, 60 male Wistar rats were randomized into 4 groups (n=15): control group, NDEA group, and two GO plus NDEA groups. The rats in GO plus NDEA groups were pretreated with GO (20 or 40 mg/kg) for 7 days. Then, all rats except those in control group were gavag...
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This study was designed to explore the protective effects of Abrus precatorius L. (Leguminosae) (AP) in HepG2 cells and N-nitrosodiethylamine (NDEA) induced hepatocellular carcinoma in Swiss albino rats. The effects of aqueous/ethanolic (50%) extract of AP on hepatic markers, haematological and histopathological parameters, and antioxidant enzymes were evaluated in NDEA ...
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Effects of garlic (Allium sativum) on circulatory lipid peroxidation and antioxidant status were evaluated in N-Nitrosodiethylamine induced hepatocarcinogenesis in male rats. Enhanced lipid peroxidation in the circulation of NNitrosodiethylamine (NDEA) treated rats was accompanied by a decrease in the levels of vitamins C and E, reduced glutathione, glutathione peroxidase, superoxide dismutase ...
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ژورنال
عنوان ژورنال: International Journal of Biological Sciences
سال: 2012
ISSN: 1449-2288
DOI: 10.7150/ijbs.3796